Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests. They ...
Sequencing diverse populations revealed over 41,000 transcripts missing in Eurocentric references, exposing ancestry bias ...
Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic ...
This study provides useful insights into addressing the question of whether the prevalence of autoimmune disease could be driven by sex differences in the T cell receptor (TCR) repertoire, correlating ...
Why Do Large B-Cell Lymphoma Patients With High Tumor Mutation Burden Relapse on CAR T-Cell Therapy?
Researchers explored this question at ASH and shared data suggesting genomic instability in tumors with high TMB likely enables them to hide from immune attack.
2don MSN
Pancreatic cancer cells 'speak the language' of organs they will later invade, study reveals
Even as they develop at their primary site, pancreatic cancer cells are already expressing the genes that will determine ...
Patients in 200 mg BID cohort had median progression free survival of 6.2 months and median overall survival of 28.1 months, comparing favorably ...
Data support initiation of a combination cohort in the ongoing Phase 1 clinical trial to evaluate ARV-393 plus glofitamab as a ...
Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...
RNA modifications are increasingly recognized as clinically relevant biomarkers, revealing immune dysregulation in autoimmune disease, early oncogenic signaling, and RNA misprocessing in ...
Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered mere transcriptional noise, lncRNAs are now known to play vital roles in ...
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