A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Ubiquitination of the C-terminus of histone ...

ABSTRACT: DNA, deoxyribonucleic acid, carrying encoded genetic information at molecular level, is the most significant discovery in the history of genetics. Previous researches on DNA included topics ...

Opening up about his inspiration for the upcoming animation, Smurfs director Chris Miller wanted to “honour the DNA of the original comics” with his take on the creatures. Barack Obama responds to ...

MEDORA, N.D. — Maggie “Mags” Scanlon is at ease as she winds through the streets of Medora, the tiny western North Dakota town where she’s spent most summers for the better part of the last decade ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Accurate genome duplication is essential for all living cells. In Escherichia coli and most other bacteria, a circular chromosome is replicated bidirectionally at high speed. Two replisomes, assembled ...

The discovery of DNA ligase by the Gellert, Lehman, Richardson, and Hurwitz teams in 1967 was a breakthrough in molecular biology. These essential enzymes maintain genome integrity and play a vital ...

A University of Iowa-led study uncovered a unique double-ring structure of the DNA repair protein RAD52 that plays a critical role in protecting stalled DNA replication in cancer cells with repair ...